Microbial infection of medical devices is one of the main causes of their failure, triggered by the microbial adhesion and biofilm formation on their surface. Biofilms are characterized by communities of microorganisms strongly attached to each other and to a biomaterial surface, embedded in an exopolymeric matrix. One important property of the biofilm matrix is the resistance to antibiotics. In this way, the development of new multifunctional antimicrobial coatings is an emergent need. This work reports the development of different coatings produced by sputtering; DLC, ZrCN, TiCN and TiN, all doped with silver to confer antibacterial activity.
Publications (click here for more information)
- C.F. Almeida Alves; F. Oliveira; I. Carvalho; A.P. Piedade; S. Carvalho. Influence of albumin on the tribological behavior of Ag-Ti (C, N) thin films for orthopedic implants, Materials Science & Engineering C: Materials for Biological Applications, 34, 22-28, 2014.
- Carvalho, I; Henriques, M.; Oliveira, J.C.; Alves, C.F.A.; Piedade, A.P.; Carvalho, S., Influence of surface features on the adhesion of Staphylococcus epidermidis to Ag-TiCN thin films, Science and Technology of Advanced Materials, 14(3), 1-10, 2013.
- Carvalho, I; Henriques, M.; Carvalho, S., New strategies to fight bacterial adhesion, Microbial Pathogens and Strategies for Combating Them: Science, Technology and Education, Formatex, Badajoz, 1, 170-178, 2013, (ISBN: 978-84-942134-1-0).
- Sánchez-López, J.C.; Abad, M.D.; Carvalho, I; Escobar Galindo, R.; Benito, N.; Ribeiro, S.; Henriques, M.; Cavaleiro, A.; Carvalho, S., Influence of silver content on the tribomechanical behavior on Ag-TiCN bioactive coatings, Surface and Coatings Technology, 206(8-9), 2192-2198, 2012.
- Henriques, M.; Susano, M.; Carvalho, I; Ferreri, I.; Carvalho, S.; Oliveira, R., Biological properties of Ti-Si-C-O-N thin films, Journal of Nano Research, 6, 99-114, 2009.